The prognostic value of DNA content measured by image cytometry in soft tissue sarcomas
نویسندگان
چکیده
منابع مشابه
Prognostic value of CD40 in adult soft tissue sarcomas.
PURPOSE The purpose is to evaluate the expression of CD40, a membrane protein predominantly expressed on B cells, dendritic cells, and macrophages, in a series of adult soft tissue sarcomas and to test its possible prognostic value. EXPERIMENTAL DESIGN CD40 expression was studied by immunohistochemistry. Correlations with other baseline characteristics of patients and tumors were analyzed wit...
متن کاملThe Clinical Value of Flow Cytometric DNA Content Analysis in Patients with Soft Tissue Sarcomas
Purpose. The purpose of this study was to evaluate: (1) the correlation between grade and ploidy or S-phase fraction (SPF), (2) the prognostic value of DNA flow cytometric study in soft tissue sarcomas.Patients /Methods. In all, 47 tissue samples from soft tissue sarcoma patients, surgically treated in the same center, were included. Flow cytometric analyses were performed according to a modifi...
متن کاملDiagnostic and prognostic value of DNA image cytometry in myelodysplasia.
The DNA content of erythropoietic cells from 10 patients with refractory anaemia (RA) with megaloblastic changes, who subsequently developed acute non-lymphoblastic leukaemia (ANL), and from seven patients with megaloblastic marrow aspirates due to pernicious anaemia were compared by DNA image cytometry. The DNA distribution, the rate of aneuploid cells exceeding 5c (5cER), and the square devia...
متن کاملSoft-tissue sarcomas of the chest wall: prognostic factors.
OBJECTIVE To evaluate factors that are predictive of outcome for patients with chest wall soft-tissue sarcomas. PATIENTS AND METHODS A retrospective review of 55 surgically treated patients, from March 1964 to October 1996. RESULTS The median age of the patients was 47.5 years (age range, 15 to 76.3 years), and 56.4% were men. The most common presenting symptom was chest wall mass in 29 pat...
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BACKGROUND The purpose of this study was to clarify the prognostic significance of peritumoral lymphocyte infiltration in the capsule of soft tissue sarcomas (STS). Multiple observations in preclinical and clinical studies have shown that the immune system has a role in controlling tumor growth and progression. Prognostic markers in potentially curable STS should guide therapy after surgical re...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 1992
ISSN: 0923-7534
DOI: 10.1093/annonc/3.suppl_2.s89